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KMID : 0356620080230010044
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Journal of Korean Society of Endocrinology
2008 Volume.23 No. 1 p.44 ~ p.50
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A Case of Pneumocystis Carinii Pneumonia and Cutaneous Nocardiosis Associated with Ectopic ACTH Syndrome
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Jeong Hee-Sun
Lee Seung-Hwan
Kim Hee-Yeon
Chu Eun-Ho
Lee Kang-Woo
Kang Mi-Ja
Kim Ji-Hyun
Kwon Hyeok-Sang
Yoon Kun-Ho
Cha Bong-Yun
Son Ho-Young
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Abstract
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Cushing`s syndrome is characterized by hypercortisolism and impairment of cell-mediated immune function, increasing the risk of opportunistic infection, as occurs in other immunocompromised groups such as organ transplant recipients, patients with lymphoreticular malignancy, or acquired immunodeficiency syndrome. We report a case of a 68-year-old woman who was affected with pneumocystis carinii pneumonia (PCP) 8 years ago and cutaneous nocardiosis this year. The patient was diagnosed with ectopic ACTH syndrome 8 years ago, but no ectopic ACTH secreting focus was found in radiologic imaging studies. She recovered from PCP and cutaneous nocardiosis after antibiotic (trimethoprim-sulfamethoxazole) administration. After the infection resolved, she underwent laparoscopic bilateral adrenalectomy and was not longer hypercortisolemic. (J Kor Endocr Soc 23:44~50, 2008)
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KEYWORD
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ectopic ACTH syndrome, pneumocystis carinii pneumonia, nocardiosis
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